The Sheslay River is a river in far northwestern British Columbia in the southeast portion of the basin of the Taku River. The river is 85 km in length from the confluence of the Hackett River to the junction of the Nahlin River, which is the commencement of the Inklin River, the main SE fork of the Taku.
The canoeable portion of the river can be accessed by fixed wheel aircraft at an airstrip at Sheslay which is at the junction of the Sheslay and Hackett Rivers. A two kilometre portage leads from the airstrip to the Sheslay.